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kinase

Synonyms

Noun
1. enzyme

Usage

Pim1 kinase identified as therapeutic target for inflammatory arthritis - Drug Target Review

Vivek Subbiah: A New Report on Clinical Activity of RET Tyrosine Kinase Inhibitor - Oncodaily

Comprehensive profiling of clinically approved kinase inhibitors reveals mutation-specific inhibitors and opportunities for drug repurposing - Nature

The allosteric landscape of the Src kinase - Science | AAAS

Kinase atlas uncovers hidden layers of cell signaling regulation - St. Jude Children's Research Hospital

Cancer's hidden escape route - EurekAlert!

Feedback control of state transition kinase activity by phosphorylation of its target PetD - Nature

Autophagolysosomal exocytosis inverts Src kinase onto the cell surface in cancer - Science | AAAS

Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies - Nature

MEK interactions tune RAF kinase sensitivity to conformation-selective inhibition - Nature

The emerging role of kinase fusion proteins in cereal immunity - Nature

Motif-based substrate mapping of the receptor-like cytoplasmic kinase BIK1 reveals novel components and regulatory nodes of plant immunity - Nature

Enhancing kinase-inhibitor activity and selectivity prediction through contrastive learning - Nature

Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis - Nature

Proteomic sensors for quantitative multiplexed and spatial monitoring of kinase signaling - Nature

Inhibitors supercharge kinase turnover through native proteolytic circuits - Nature

Pharmacophore-driven kinase profiling applied to the PKIS2 chemogenomic dataset - Nature

Exploring the conformational landscape of adenylate kinase and beyond with protein folding models - Nature

The kinase domain of RIPK3 tunes its scaffolding functions - Cell Death & Differentiation - Nature

Double whammy: drugs that inhibit kinase enzymes also speed up their disposal - Nature

Kinase inhibitors can be targeted protein degraders too - C&EN

Kinase interaction analysis predicts actions of the WNK-OSR1/SPAK pathway | Communications Biology - Nature

PAK4 phosphorylates cyclin-dependent kinase 2 to promote the G - Nature

Molecular recording of cellular protein kinase activity with chemical labeling - Nature

Protein Kinase C promotes peroxisome biogenesis and peroxisome–endoplasmic reticulum interaction - Rockefeller University Press

Discovery of effectors for casein kinase signaling in the African trypanosome | Scientific Reports - Nature

Advancements in Protein Kinase Inhibitors: From Discovery to Clinical Applications - Science Partner Journals

A web portal for exploring kinase-substrate interactions | npj Systems Biology and Applications - Nature

Human DNA-dependent protein kinase activation mechanism - Nature

The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound - Nature

A bi-kinase module sensitizes and potentiates plant immune signaling - Science | AAAS

Illuminating understudied kinases: a generalizable biosensor development method applied to protein kinase N - Nature

Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering - PNAS

Kinase drug discovery 20 years after imatinib: progress and future directions - Nature

Light-gated integrator for highlighting kinase activity in living cells - Nature

Comprehensive evaluation of phosphoproteomic-based kinase activity inference - Nature

Protein Kinase A Is a Master Regulator of Physiological and Pathological Cardiac Hypertrophy - American Heart Association Journals

Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers - Nature

Transitions to catalytically inactive conformations in EGFR kinase - PNAS

Magnesium induced structural reorganization in the active site of adenylate kinase - Science | AAAS

Robust inference of kinase activity using functional networks - Nature

Tandem kinase proteins across the plant kingdom - Nature

Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation - Nature

Mechanism of activation and autophosphorylation of a histidine kinase - Nature

Requirement of protein kinase D1 for pathological cardiac remodeling - PNAS

Crowdsourced mapping of unexplored target space of kinase inhibitors - Nature

Kinase inhibition profiles as a tool to identify kinases for specific phosphorylation sites - Nature

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases - PNAS

Research shows why cancer stops responding to kinase-blocking drugs and comes back stronger - National Science Foundation (.gov)

Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation - Science | AAAS

A Structurally-Validated Multiple Sequence Alignment of 497 Human Protein Kinase Domains - Nature

The Protein Kinase Complement of the Human Genome - Science | AAAS

Kinome screening identifies integrated stress response kinase EIF2AK1/HRI as a negative regulator of PINK1 mitophagy signaling - Science | AAAS

Targeting cancer with small molecule kinase inhibitors - Nature

Cellular functions of the protein kinase ATM and their relevance to human disease - Nature

Subcellular partitioning of protein kinase activity revealed by functional kinome profiling - Nature

Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter - Nature

Trends in kinase drug discovery: targets, indications and inhibitor design - Nature

De novo design of tyrosine and serine kinase-driven protein switches - Nature

Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure - The New England Journal of Medicine

HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation - Nature

PAS kinase: An evolutionarily conserved PAS domain-regulated serine/threonine kinase - PNAS

A historical overview of protein kinases and their targeted small molecule inhibitors - ScienceDirect.com

Discovering the first tyrosine kinase - PNAS

Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology - Nature

Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase - Nature

Protein Kinase Inhibitor Peptide as a Tool to Specifically Inhibit Protein Kinase A - Frontiers

Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors - Nature

Targets mapped for almost all human kinase enzymes - Nature

Deep learning enables rapid identification of potent DDR1 kinase inhibitors - Nature

Kinase drug discovery 20 years after imatinib - Nature

Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival - Nature

Zooming in on protons: Neutron structure of protein kinase A trapped in a product complex - Science | AAAS

S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions - Nature

Proteome-wide screening for mitogen-activated protein kinase docking motifs and interactors - Science | AAAS

Aurora A kinase activation: Different means to different ends - Rockefeller University Press

The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis - Nature

Nuclear translocation of 3′-phosphoinositide-dependent protein kinase 1 (PDK-1): A potential regulatory mechanism for PDK-1 function - PNAS

Evidence that phytochrome functions as a protein kinase in plant light signalling - Nature

Comprehensive analysis of kinase inhibitor selectivity - Nature

Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells - PNAS

A dynamically coupled allosteric network underlies binding cooperativity in Src kinase - Nature

Protein kinase N controls a lysosomal lipid switch to facilitate nutrient signalling via mTORC1 - Nature

A chemical switch for inhibitor-sensitive alleles of any protein kinase - Nature

Activity-dependent CREB phosphorylation: Convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway - PNAS

Cell pole–specific activation of a critical bacterial cell cycle kinase - PNAS

Revisiting protein kinase–substrate interactions: Toward therapeutic development - Science | AAAS

Comprehensive characterization of the Published Kinase Inhibitor Set - Nature

Protein kinase C controls lysosome biogenesis independently of mTORC1 - Nature

RedOx regulation of LRRK2 kinase activity by active site cysteines - Nature

Selective inhibition of the kinase DYRK1A by targeting its folding process - Nature

IκB kinase ε and TANK-binding kinase 1 activate AKT by direct phosphorylation - PNAS

Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression - PNAS

Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses - Nature

The Arabidopsis SOS2 protein kinase physically interacts with and is activated by the calcium-binding protein SOS3 - PNAS

Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56δ subunit - PNAS

A dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-α signaling - PNAS

Ternary structure reveals mechanism of a membrane diacylglycerol kinase - Nature

Mechanoenzymatics of titin kinase - PNAS

Making New Connections : Role of ERK/MAP Kinase Signaling in Neuronal Plasticity - ScienceDirect.com

Foreign Language Equivalents

Foreign Language Equivalents of 'kinase'
Language	Equivalent		Language	Equivalent
French			Spanish

Misspellings - Typos

kiase,   kinnase,   iknase,   kinaase,   kinasee,   jinase,   kkinase,   kinasr,   kimase,   kinsse,   knase,   kibase,   konase,   kinsae,   kinaae,   inase,   kinse,   kiinase,   kinade,   kinas,   kinasse,   kinasw,   kniase,   kianse,   kinaes,   linase,   kinae,   kunase

Words Starting with Letter - 'A'

a	a battery	a billion
a bit	a bit much	a capella singing
a cappella singing	a couple of	a few
a fortiori	a good deal	a great deal
a horizon	a hundred	a hundred and one
a hundred thousand	a hundred times	a kempis
a la carte	a la mode	a level
a little	a lot	a million

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