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caspase
Synonyms
Noun
1. protease
2. peptidase, proteinase, proteolytic enzyme
Usage
Chemotherapy-induced activation of caspase-1 and IL-1α release by cancer cells remotely skews myelopoiesis to drive pro tumorigenic systemic neutrophil-dominant inflammation - Nature
Caspase-3 cleaves and activates the NADase SARM1 to promote apoptosis, linking two cell death mechanisms - PNAS
Caspase 5c amplifies Wnt via APC cleavage to promote intestinal homeostasis - Nature
NLRP3/Caspase-1 Regulate Macrophage Efferocytosis by Modulating ADAM17-Mediated MerTK Cleavage in Liver Ischemia–Reperfusion Injury - Science Partner Journals
Dipeptidyl Peptidase 4 Mediated Caspase-8 Affects Cognitive Impairment in Mice With Alzheimer's Disease - Wiley
Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection - Nature
Caspase-8-mediated CYLD cleavage boosts LPS-induced endotoxic shock - Nature
Discovery of spectosis supports the key role of caspase-8 in determining the type of cell death in mature erythrocytes and erythrocyte death-driven immunogenicity - Nature
Caspase-8 comes in from the CYLD - Nature
cFLIP suppresses caspase-1- and MLKL-independent perinatal lethality driven by auto-processing impaired caspase-8 D387A | Cell Death & Differentiation - Nature
Caspase 6 deficiency exacerbates inflammatory bowel disease via enterocyte necroptosis and bacterial translocation - Nature
Atypical contribution of caspase-3 to melanoma cancer cell motility by regulation of coronin 1B activity - Nature
A non-apoptotic caspase-8–meteorin pathway in hepatocytes promotes MASH fibrosis - Nature
Non-genetic inactivation of caspase-3 and P53 increases cancer cell fitness by PDIA4 redistribution | Oncogene - Nature
Shooting for the stars: caspase-8–meteorin in MASH and fibrosis - Nature
Salidroside ameliorates diabetic amyotrophy by targeting Caspase-3 to inhibit apoptosis - Nature
Regulation of inflammatory processes by caspases - Nature
Caspase-2 is a condensate-mediated deubiquitinase in protein quality control - Nature
Nonapoptotic caspase-3 guides C1q-dependent synaptic phagocytosis by microglia - Nature
Caspase-2 protects against ferroptotic cell death - Cell Death & Disease - Nature
Arginine methylation of caspase-8 controls life/death decisions in extrinsic apoptotic networks - Nature
Caspase-7 activates ASM to repair gasdermin and perforin pores - Nature
A long way to go: caspase inhibitors in clinical use - Nature
Caspases as master regulators of programmed cell death: apoptosis, pyroptosis and beyond - Nature
heterodimer enhances complex II assembly and elimination of pancreatic cancer cells - Nature
Caspases: structural and molecular mechanisms and functions in cell death, innate immunity, and disease - Nature
Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7 - Science | AAAS
The prodomain of caspase-3 regulates its own removal and caspase activation - Nature
The p53-caspase-2 axis in the cell cycle and DNA damage response - Nature
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death - Nature
Caspase 9-induced apoptosis enables efficient fetal cell ablation and disease modeling - Nature
Caspase-1 initiates apoptosis in the absence of gasdermin D - Nature
Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation - Nature
Drug-induced oxidative stress actively prevents caspase activation and hepatocyte apoptosis - Nature
Caspases and their substrates - Cell Death & Differentiation - Nature
Caspase 3 activity is required for skeletal muscle differentiation - PNAS
Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells - Science | AAAS
Apoptosis regulation by subcellular relocation of caspases - Nature
Caspase-3 promotes oncogene-induced malignant transformation via EndoG-dependent Src-STAT3 phosphorylation - Nature
Dopaminergic neurons lacking Caspase-3 avoid apoptosis but undergo necrosis after MPTP treatment inducing a Galectin-3-dependent selective microglial phagocytic response - Nature
Short IL-18 generated by caspase-3 cleavage mobilizes NK cells to suppress tumor growth - Nature
Caspase involvement in autophagy - Nature
Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate - Nature
Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma - Nature
Caspase-11 promotes allergic airway inflammation - Nature
Caspase 3/caspase-activated DNase promote cell differentiation by inducing DNA strand breaks - PNAS
Ally or traitor: the dual role of p62 in caspase-2 regulation - Cell Death & Disease - Nature
Differential roles of caspase-1 and caspase-11 in infection and inflammation - Nature
A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death | Scientific Reports - Nature
Identification of Allosteric Inhibitors against Active Caspase-6 - Nature
Inflammasome activation leads to Caspase-1–dependent mitochondrial damage and block of mitophagy - PNAS
TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis | Cell Death Discovery - Nature
Apoptotic caspase inhibits innate immune signaling by cleaving NF-κBs in both Mammals and Flies - Nature
Crystal structure of caspase-11 CARD provides insights into caspase-11 activation - Nature
Caspase-10: a molecular switch from cell-autonomous apoptosis to communal cell death in response to chemotherapeutic drug treatment - Nature
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin - Nature
Evolution of caspase-mediated cell death and differentiation: twins separated at birth - Nature
Caspase-dependent non-apoptotic processes in development - Nature
Inflammatory caspase substrate specificities - ASM Journals
Caspase-2-mediated cell death is required for deleting aneuploid cells - Nature
Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis - Nature
Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide - Nature
Genuine selective caspase-2 inhibition with new irreversible small peptidomimetics - Nature
Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis - Nature
Caspase-2 Substrates: To Apoptosis, Cell Cycle Control, and Beyond - Frontiers
Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion | Cell Death & Differentiation - Nature
Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria - Nature
Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia - Nature
Recognition and maturation of IL-18 by caspase-4 noncanonical inflammasome - Nature
Akt1 and dCIZ1 promote cell survival from apoptotic caspase activation during regeneration and oncogenic overgrowth - Nature
Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme - PNAS
The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions - Nature
Non-lethal roles of the initiator caspase Dronc in Drosophila - Frontiers
Activity of caspase-8 determines plasticity between cell death pathways - Nature
Old, new and emerging functions of caspases - Cell Death & Differentiation - Nature
The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities - Nature
p62/SQSTM1-induced caspase-8 aggresomes are essential for ionizing radiation-mediated apoptosis - Nature
Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition - Nature
Visualization of caspase-3-like activity in cells using a genetically encoded fluorescent biosensor activated by protein cleavage - Nature
The road to death: Caspases, cleavage, and pores - Science | AAAS
Caspase-10 is an initiator caspase in death receptor signaling - PNAS
Caspase-8 cleaves its substrates from the plasma membrane upon CD95-induced apoptosis - Nature
Caspase-2: the orphan caspase - Nature
Neuronal caspase-3 signaling: not only cell death - Nature
Spatial sequestration of activated-caspase 3 in aggresomes mediates resistance of neuroblastoma cell to bortezomib treatment - Nature
Single-cell imaging of inflammatory caspase dimerization reveals differential recruitment to inflammasomes - Nature
Local Pruning of Dendrites and Spines by Caspase-3-Dependent and Proteasome-Limited Mechanisms - Journal of Neuroscience
Dronc-independent basal executioner caspase activity sustains Drosophila imaginal tissue growth - PNAS
Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis - PNAS
Dimer formation drives the activation of the cell death protease caspase 9 - PNAS
Lysosomes, caspase-mediated apoptosis, and cytoplasmic activation of P21, but not cell senescence, participate in a redundant fashion in embryonic morphogenetic cell death - Nature
Caspase activation pathways: some recent progress - Nature
A Caspase Cascade Regulating Developmental Axon Degeneration - Journal of Neuroscience
Chemotherapy-induced executioner caspase activation increases breast cancer malignancy through epigenetic de-repression of CDH12 - Nature
Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate - Nature
Caspase-3/-7-Specific Metabolic Precursor for Bioorthogonal Tracking of Tumor Apoptosis - Nature
The biochemical mechanism of caspase-2 activation - Nature
Caspase-3 cleaves hnRNP K in erythroid differentiation - Nature
The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis - Nature
Discovery of a caspase cleavage motif antibody reveals insights into noncanonical inflammasome function - PNAS
Foreign Language Equivalents
Foreign Language Equivalents of 'caspase'
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Misspellings - Typos
cas[ase, caspse, caspsse, caspas, caspasse, acspase, casspase, csapase, aspase, caspade, caspaase, casase, casoase, caspae, caspasee, cspase, casapse, xaspase, capase, caaspase, caspasr, capsase, vaspase, caspaes, caapase, casppase, ccaspase, caspsae, csspase, caspaae, cadpase, caspasw
Words Starting with Letter - 'A'
a
a battery
a billion
a bit
a bit much
a capella singing
a cappella singing
a couple of
a few
a fortiori
a good deal
a great deal
a horizon
a hundred
a hundred and one
a hundred thousand
a hundred times
a kempis
a la carte
a la mode
a level
a little
a lot
a million
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